The tour begins at Museumplein, redesigned in the 1990s by landscape architect Sven-Ingvar Andersson. The square replaced a former cobblestone road once known as the shortest highway in the Netherlands, and now features a rectangular pond marking that original junction.

The route passes Lizzy Cottage, a 1902 building by A.W. Weissman featuring a gold frieze decorated with putti figures above the bay window. Nearby, the audio explains Amsterdam's diamond industry, which at its peak employed over 700 polishing wheels used on stones including the Cullinan diamond.

Walkers pass the Van Gogh Museum, whose main building was completed in 1973 to a design by Gerrit Rietveld, a central figure in the De Stijl movement. Steps away, the Stedelijk Municipal Museum presents a textbook example of Dutch Renaissance architecture, with its characteristic narrow profile, stepped gables, and ornamental stonework.

The Crystal Houses building on P.C. Hooftstraat demonstrates how contemporary architects Gietermans and van Dijk and MVRDV integrated glass bricks into a protected monumental facade. The route continues toward the Vondelpark bridge, designed in 1936 by architect Piet Kramer to link Nieuw-West and Nieuw-Zuid without routing traffic through the park.

At house number 37, two gold-colored memorial stones mark the former home of Isidor and Renee Drievoet, personally laid by German artist Gunter Demnig. The nearby Zevenlanden ensemble of seven houses, completed in 1894, presents seven distinct European architectural styles side by side on a single street.

The tour concludes at Max Euweplein, a square named in honor of Max Euwe, the only Dutch player ever to hold the world chess championship title. The oversized outdoor chessboard at the corner of the square remains one of Amsterdam's most recognizable public art installations.